AQA GCSE · Biology 8461

Monoclonal antibodies: Practice Questions

5 multiple-choice questions marked as you go, and 3 written questions with worked solutions. All on Monoclonal antibodies.

8 questions16 marksFree, no account

Question 1

1 mark

During the production of monoclonal antibodies, mouse lymphocytes are combined with a specific type of cell to create a hybridoma. What is this second cell type?

Question 2

1 mark

In the production of monoclonal antibodies, which two types of cells are fused to create a hybridoma cell?

Question 3

1 mark

In the treatment of cancer, monoclonal antibodies can be bound to a radioactive substance or a toxic drug.
What is the specific advantage of using this method over traditional chemotherapy?

Question 4

1 mark

In the production of monoclonal antibodies, which type of animal cell is stimulated to produce the required antibodies before being fused with a tumor cell?

Question 5

1 mark

Monoclonal antibodies are used in research to locate specific molecules in a cell. Which substance is typically bound to the antibody to allow this visualization?

Question 6

2 marks

Briefly describe the two components that are fused together to form a hybridoma cell during the production of monoclonal antibodies.

Write your answer out first, then check it against the worked solution.

Question 7

4 marks

Explain how monoclonal antibodies are used to treat cancer by delivering toxic drugs directly to specific cells without harming healthy tissue.

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Question 8

5 marks

A student uses a monoclonal antibody test kit to identify a plant pathogen.
Explain the biological principle of how these antibodies allow for the specific detection of only one type of pathogen in a sample containing many microorganisms.

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