Cambridge International AS Level · Biology (9700)

Immunity: Practice Questions

5 multiple-choice questions marked as you go, and 5 written questions with worked solutions. All on Immunity.

10 questions21 marksFree, no account
Question 1
1 mark

What is the definitive characteristic of passive immunity?

Question 2
1 mark

During a primary immune response, which sequence of events occurs after a macrophage has engulfed a pathogen?

Question 3
1 mark

In a secondary immune response, the concentration of antibodies in the blood rises much more steeply than in the primary response.
What biological factor is primarily responsible for this difference?

Question 4
1 mark

Which statement correctly describes a difference between the mode of action of neutrophils and macrophages during an immune response?

Question 5
1 mark

Which feature of antibody molecules allows them to bind to two identical antigens simultaneously?

Question 6
2 marks

State the role of memory cells in the secondary immune response upon re-exposure to the same non-self antigen.

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Question 7
3 marks

Explain how artificial active immunity is acquired following a vaccination programme.

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Question 8
2 marks

Distinguish between a self antigen and a non-self antigen.

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Question 9
4 marks

The diagram represents the structure of an antibody molecule (immunoglobulin G).

(a) State the specific term given to region X and explain how its structure enables the antibody to perform its function.
(b) State the role of the hinge region labeled Y.
(c) Name the type of covalent bond labeled Z that holds the polypeptide chains together.

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Question 10
5 marks

Monoclonal antibodies are widely used in medical diagnosis and targeted therapy.

(a) Outline the steps involved in the production of monoclonal antibodies using the hybridoma method, starting from the immunization of an animal to the collection of the antibodies.
(b) Explain why hybridoma cells, rather than normal plasma cells or myeloma cells alone, are required for the industrial production of monoclonal antibodies.
(c) State one advantage of using monoclonal antibodies in the treatment of diseases, such as cancer, compared to traditional chemotherapy.

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