Oxford AQA International A-level · Biology (9610)

HIV as an example of a human disease caused by a virus: Practice Questions

3 multiple-choice questions marked as you go, and 5 written questions with worked solutions. All on HIV as an example of a human disease caused by a virus.

8 questions24 marksFree, no account

Question 1

1 mark

The Human Immunodeficiency Virus (HIV) is classified as a retrovirus. Which component of the HIV particle is responsible for the initial attachment to the host cell?

Question 2

1 mark

Which sequence of events correctly describes the replication of HIV after the viral contents have entered a CD4 helper T-cell?

Question 3

1 mark

During the replication cycle of HIV, the viral enzyme integrase plays a critical role. What is the specific function of this enzyme?

Question 4

3 marks

Explain why HIV is specifically able to bind to and enter CD4 helper T-cells but not other cell types like muscle cells.

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Question 5

5 marks

Explain how protease inhibitors prevent the production of functional HIV particles and describe the impact this has on the viral life cycle.

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Question 6

3 marks

Describe the specific role of the enzyme reverse transcriptase in the replication cycle of HIV.

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Question 7

4 marks

Describe the structure of the Human Immunodeficiency Virus (HIV) and explain how the specific role of its surface glycoproteins allows the virus to infect only certain types of human cells.

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Question 8

6 marks

HIV is a retrovirus that contains the enzyme reverse transcriptase.
(a) Describe the process catalyzed by reverse transcriptase once the viral RNA enters the host cell. (2 points)
(b) Explain the role of the enzyme integrase in the replication cycle of HIV. (2 points)
(c) Why is the integration of viral genetic material into the host chromosome a significant factor in the long-term nature of the infection? (2 points)

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