Oxford AQA International A-level · Biology (9610)

Hormones and the control of blood glucose concentration: Practice Questions

4 multiple-choice questions marked as you go, and 5 written questions with worked solutions. All on Hormones and the control of blood glucose concentration.

9 questions24 marksFree, no account

Question 1

1 mark

Which hormone is primarily responsible for activating enzymes that convert glycogen to glucose (glycogenolysis) in the liver when blood glucose levels are low?

Question 2

1 mark

In the second messenger model of hormone action, what is the specific role of the enzyme adenyl cyclase when adrenaline binds to its receptor?

Question 3

1 mark

Which of the following best explains how insulin reduces blood glucose concentration after a meal?

Question 4

1 mark

Which of the following processes involves the liver converting non-carbohydrates, such as glycerol and amino acids, into glucose?

Question 5

4 marks

Explain how the second messenger model is used by glucagon to trigger the hydrolysis of glycogen in liver cells.

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Question 6

5 marks

A patient is diagnosed with Type 2 diabetes. Despite high levels of insulin in the blood, their blood glucose remains elevated.

Suggest how a defect in the signal transduction pathway, following the binding of insulin to its receptor, prevents the lowering of blood glucose levels.

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Question 7

3 marks

When blood glucose concentration falls, glucagon is secreted by the pancreas.

Identify two specific non-carbohydrate sources that can be converted into glucose by the liver under the influence of this hormone.

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Question 8

3 marks

Blood glucose levels are strictly regulated by the pancreas to ensure cellular energy needs are met while maintaining blood water potential.

(a) Name the specific endocrine tissue in the pancreas responsible for the production of glucose-regulating hormones.
(b) Identify the specific cells within this tissue that secrete insulin and glucagon.
(c) State two ways in which glucose is added to the blood during the normal daily cycle of a healthy individual.

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Question 9

5 marks

A student investigates the hormonal response to a high-carbohydrate meal in a healthy volunteer. Within 60 minutes, the blood glucose concentration rises and then begins to return to its original level due to the action of insulin.

(a) Describe how insulin leads to the inclusion of more glucose transport proteins (GLUT4) in the surface membranes of target cells.
(b) Aside from membrane transport, explain how insulin affects intracellular enzymes to ensure blood glucose remains low.
(c) Suggest why a failure in this regulatory mechanism could lead to dehydration of the body's cells.

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