Question 1 · Free-Response
9 marksA certain biochemical compound accumulates in an experimental bioreactor starting at time \(t = 0\) hours. The total mass of the compound in the bioreactor is modeled by the differentiable function \(M\) defined by \(M(t) = 9.6 \arctan(0.25t)\), where \(M(t)\) is measured in grams and \(t\) is measured in hours for \(t \ge 0\). It can be shown that \(M'(t) = \frac{38.4}{16 + t^2}\).
(Note: Your calculator should be in radian mode.)
A. Find the average mass of the compound in the bioreactor from time \(t = 0\) to time \(t = 6\) hours. Show the setup for your calculations.
B. Find the time \(t\) when the instantaneous rate of change of \(M\) equals the average rate of change of \(M\) over the time interval \(0 \le t \le 6\). Show the setup for your calculations.
C. Assume that the compound continues to accumulate according to the given model for all times \(t > 0\). Write a limit expression that describes the end behavior of the rate of change of the mass of the compound in the bioreactor. Evaluate this limit expression.
D. At time \(t = 6\) hours after the process begins, a neutralizing agent begins filtering the compound from the bioreactor. The function \(B\), defined by \(B(t) = M(t) - \int_6^t 0.15 \ln(x^2 + 1)\, dx\), models the mass of the compound in the bioreactor over the time interval \(6 \le t \le 24\). At what time \(t\), for \(6 \le t \le 24\), does \(B\) attain its maximum value? Justify your answer.
(Note: Your calculator should be in radian mode.)
A. Find the average mass of the compound in the bioreactor from time \(t = 0\) to time \(t = 6\) hours. Show the setup for your calculations.
B. Find the time \(t\) when the instantaneous rate of change of \(M\) equals the average rate of change of \(M\) over the time interval \(0 \le t \le 6\). Show the setup for your calculations.
C. Assume that the compound continues to accumulate according to the given model for all times \(t > 0\). Write a limit expression that describes the end behavior of the rate of change of the mass of the compound in the bioreactor. Evaluate this limit expression.
D. At time \(t = 6\) hours after the process begins, a neutralizing agent begins filtering the compound from the bioreactor. The function \(B\), defined by \(B(t) = M(t) - \int_6^t 0.15 \ln(x^2 + 1)\, dx\), models the mass of the compound in the bioreactor over the time interval \(6 \le t \le 24\). At what time \(t\), for \(6 \le t \le 24\), does \(B\) attain its maximum value? Justify your answer.
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Worked solution
Part A
The average mass of the compound over the interval \(0 \le t \le 6\) is given by the average value formula:
$$\text{Average mass} = \frac{1}{6 - 0} \int_0^6 M(t)\, dt = \frac{1}{6} \int_0^6 9.6 \arctan(0.25t)\, dt$$
Evaluating the definite integral using a graphing calculator:
$$\frac{1}{6}(33.97874) = 5.663123$$
From time \(t = 0\) to \(t = 6\) hours, the average mass of the compound in the bioreactor was \(5.663\) grams.
Part B
The average rate of change of \(M\) over the interval \([0, 6]\) is:
$$\frac{M(6) - M(0)}{6 - 0} = \frac{9.6 \arctan(1.5) - 0}{6} = 1.572470$$
To find when the instantaneous rate of change equals the average rate of change, set \(M'(t)\) equal to this value:
$$M'(t) = \frac{38.4}{16 + t^2} = 1.572470$$
Using a calculator to solve for \(t\) on \(0 \le t \le 6\):
$$16 + t^2 = 24.420177 \implies t^2 = 8.420177 \implies t = 2.901754$$
The instantaneous rate of change of \(M\) equals the average rate of change at time \(t = 2.902\) hours.
Part C
The end behavior of the rate of change of the mass is described by the limit as \(t \to \infty\) of \(M'(t)\):
$$\lim_{t \to \infty} M'(t) = \lim_{t \to \infty} \frac{38.4}{16 + t^2} = 0$$
Part D
By the Fundamental Theorem of Calculus:
$$B'(t) = M'(t) - 0.15 \ln(t^2 + 1) = \frac{38.4}{16 + t^2} - 0.15 \ln(t^2 + 1)$$
Setting \(B'(t) = 0\) on the interval \(6 \le t \le 24\):
$$\frac{38.4}{16 + t^2} = 0.15 \ln(t^2 + 1) \implies t = 7.023547$$
Testing critical points and endpoints on \(6 \le t \le 24\):
- \(B(6) = M(6) = 9.434820\)
- \(B(7.023547) = M(7.023547) - \int_6^{7.023547} 0.15 \ln(x^2 + 1)\, dx \approx 10.117178 - 0.603099 = 9.514079\)
- \(B(24) = M(24) - \int_6^{24} 0.15 \ln(x^2 + 1)\, dx \approx 13.504104 - 15.688267 = -2.184163\)
Alternatively, \(B'(t) > 0\) for \(6 \le t < 7.024\) and \(B'(t) < 0\) for \(7.024 < t \le 24\). Therefore, \(B\) attains its absolute maximum at time \(t = 7.024\) (or \(7.023\)) hours.
The average mass of the compound over the interval \(0 \le t \le 6\) is given by the average value formula:
$$\text{Average mass} = \frac{1}{6 - 0} \int_0^6 M(t)\, dt = \frac{1}{6} \int_0^6 9.6 \arctan(0.25t)\, dt$$
Evaluating the definite integral using a graphing calculator:
$$\frac{1}{6}(33.97874) = 5.663123$$
From time \(t = 0\) to \(t = 6\) hours, the average mass of the compound in the bioreactor was \(5.663\) grams.
Part B
The average rate of change of \(M\) over the interval \([0, 6]\) is:
$$\frac{M(6) - M(0)}{6 - 0} = \frac{9.6 \arctan(1.5) - 0}{6} = 1.572470$$
To find when the instantaneous rate of change equals the average rate of change, set \(M'(t)\) equal to this value:
$$M'(t) = \frac{38.4}{16 + t^2} = 1.572470$$
Using a calculator to solve for \(t\) on \(0 \le t \le 6\):
$$16 + t^2 = 24.420177 \implies t^2 = 8.420177 \implies t = 2.901754$$
The instantaneous rate of change of \(M\) equals the average rate of change at time \(t = 2.902\) hours.
Part C
The end behavior of the rate of change of the mass is described by the limit as \(t \to \infty\) of \(M'(t)\):
$$\lim_{t \to \infty} M'(t) = \lim_{t \to \infty} \frac{38.4}{16 + t^2} = 0$$
Part D
By the Fundamental Theorem of Calculus:
$$B'(t) = M'(t) - 0.15 \ln(t^2 + 1) = \frac{38.4}{16 + t^2} - 0.15 \ln(t^2 + 1)$$
Setting \(B'(t) = 0\) on the interval \(6 \le t \le 24\):
$$\frac{38.4}{16 + t^2} = 0.15 \ln(t^2 + 1) \implies t = 7.023547$$
Testing critical points and endpoints on \(6 \le t \le 24\):
- \(B(6) = M(6) = 9.434820\)
- \(B(7.023547) = M(7.023547) - \int_6^{7.023547} 0.15 \ln(x^2 + 1)\, dx \approx 10.117178 - 0.603099 = 9.514079\)
- \(B(24) = M(24) - \int_6^{24} 0.15 \ln(x^2 + 1)\, dx \approx 13.504104 - 15.688267 = -2.184163\)
Alternatively, \(B'(t) > 0\) for \(6 \le t < 7.024\) and \(B'(t) < 0\) for \(7.024 < t \le 24\). Therefore, \(B\) attains its absolute maximum at time \(t = 7.024\) (or \(7.023\)) hours.
Marking scheme
Part A (2 points):
- Point 1 (P1): Average value formula (correct definite integral with evidence of division by 6).
- Point 2 (P2): Answer (5.663 or 5.664).
Part B (2 points):
- Point 3 (P3): Average rate of change expression or value (\(\frac{M(6)-M(0)}{6}\) or 1.572).
- Point 4 (P4): Answer with supporting equation (\(t = 2.902\)).
Part C (2 points):
- Point 5 (P5): Limit expression (\(\lim_{t \to \infty} M'(t)\) or \(\lim_{t \to \infty} \frac{38.4}{16 + t^2}\)).
- Point 6 (P6): Value (0).
Part D (3 points):
- Point 7 (P7): Considers \(B'(t) = 0\) (or \(M'(t) - 0.15 \ln(t^2 + 1) = 0\)).
- Point 8 (P8): Justification (Candidates test evaluating \(B(t)\) at \(t = 6, 7.024, 24\) OR global sign analysis of \(B'(t)\)).
- Point 9 (P9): Answer with supporting work (\(t = 7.024\) or \(7.023\)).
- Point 1 (P1): Average value formula (correct definite integral with evidence of division by 6).
- Point 2 (P2): Answer (5.663 or 5.664).
Part B (2 points):
- Point 3 (P3): Average rate of change expression or value (\(\frac{M(6)-M(0)}{6}\) or 1.572).
- Point 4 (P4): Answer with supporting equation (\(t = 2.902\)).
Part C (2 points):
- Point 5 (P5): Limit expression (\(\lim_{t \to \infty} M'(t)\) or \(\lim_{t \to \infty} \frac{38.4}{16 + t^2}\)).
- Point 6 (P6): Value (0).
Part D (3 points):
- Point 7 (P7): Considers \(B'(t) = 0\) (or \(M'(t) - 0.15 \ln(t^2 + 1) = 0\)).
- Point 8 (P8): Justification (Candidates test evaluating \(B(t)\) at \(t = 6, 7.024, 24\) OR global sign analysis of \(B'(t)\)).
- Point 9 (P9): Answer with supporting work (\(t = 7.024\) or \(7.023\)).