第 1 題
1 分According to the principles of cell specialisation, which of the following statements correctly describes the distribution of stem cells in humans?
Oxford AQA International A-level · Biology (9610)
轉錄與轉譯的調控：練習題
5 條多項選擇題即時批改，另有 5 條文字題附完整解題步驟，全部圍繞「轉錄與轉譯的調控」。
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第 2 題
1 分Which of the following best explains how decreased acetylation of histones leads to the inhibition of transcription?
第 3 題
1 分What is the primary mechanism by which small interfering RNA (siRNA) regulates gene expression within a cell?
第 4 題
1 分Abnormal epigenetic changes can lead to the development of cancer. Which combination of changes would most likely result in the inactivation of a tumour suppressor gene?
第 5 題
1 分Which statement best distinguishes the mechanism of RNA interference (RNAi) from the mechanism of epigenetic control by DNA methylation?
第 6 題
3 分Explain how increased methylation of DNA inhibits the transcription of a specific target gene.
先自己寫一次答案，再對照解題步驟。
第 7 題
5 分Abnormal epigenetic modifications are frequently observed in malignant cells. Explain why decreased acetylation of histones associated with a tumour suppressor gene would result in a selective advantage for a growing tumour.
先自己寫一次答案，再對照解題步驟。
第 8 題
3 分Contrast multipotent and unipotent stem cells in terms of their differentiation potential and identify one specific tissue in a mature mammal where unipotent stem cells are typically found.
先自己寫一次答案，再對照解題步驟。
第 9 題
4 分Although every somatic cell in a mammal contains the same genome, different cell types express different genes. This process is essential for the development of a complex organism.
(a) State what is meant by the term totipotent and explain why these cells are only present for a limited period in mammalian development. (2 points)
(b) Describe how transcription factors regulate the expression of specific genes, allowing a cell to become specialised. (2 points)
先自己寫一次答案，再對照解題步驟。
第 10 題
4 分Describe the mechanism by which small interfering RNA (siRNA) regulates gene expression at the translational level. In your answer, explain how the process results in the inhibition of a specific target protein.
先自己寫一次答案，再對照解題步驟。
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