IB Diploma Programme (DP) - SL & HL · Biology
その場で採点される選択問題 5 問と、解説つきの記述問題 3 問。すべて「D2.2 Gene expression (Cells, HL)」からの出題です。
In eukaryotic organisms, the level of DNA methylation in the promoter region of a gene is often associated with its transcriptional activity. What is the most likely effect of a high degree of DNA methylation on the expression of a specific gene?
Studies of monozygotic (identical) twins have shown that as they age, their gene expression patterns become increasingly different despite having identical DNA sequences. What is the most likely cause of this phenomenon?
In eukaryotic gene regulation, how do nucleosomes specifically influence the rate of transcription?
In the regulation of eukaryotic gene expression, what is the specific role of spliceosomes during post-transcriptional modification?
During the process of transcription in eukaryotes, in which direction is the mRNA strand elongated and which DNA strand serves as the template?
Explain the functional role of the promoter sequence in determining both the orientation and the specific start point of transcription for a eukaryotic gene.
まず自分で答えを書いてから、解説と照らし合わせましょう。
Discuss how the length of the 3' poly-A tail and the presence of the 5' cap collectively regulate the half-life and translational efficiency of mRNA in the cytoplasm.
まず自分で答えを書いてから、解説と照らし合わせましょう。
Explain the various levels at which gene expression can be regulated in eukaryotic cells, from transcriptional control to post-translational modifications. Illustrate with specific examples for at least three different regulatory mechanisms (e.g., DNA methylation, histone acetylation, microRNAs, alternative splicing, protein degradation), detailing how each mechanism affects the amount or activity of the final protein product. (HL topic)
まず自分で答えを書いてから、解説と照らし合わせましょう。
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