Which reagent and condition can be used to achieve complete hydrolysis of a protein into its individual \(\alpha\)-amino acids?
GCE A-Level - Higher 2 (H2) · Chemistry (9476)
Proteins:練習問題
その場で採点される選択問題 4 問と、解説つきの記述問題 2 問。すべて「Proteins」からの出題です。
A tripeptide is formed from the condensation of three molecules of glycine (\(H_2NCH_2COOH\)). What is the molecular formula of this tripeptide?
Consider the structure of a protein. Which of the following statements regarding the hydrolysis of peptide bonds is incorrect?
A polypeptide with the sequence Ala-Gly-Val is completely hydrolysed using concentrated \(HCl(aq)\) and heat. Which of the following species would be present in the reaction mixture at the end of the process?
Describe the chemical reaction that occurs when a protein is heated under reflux with concentrated aqueous \(HCl\).
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Proteins are biological macromolecules essential for life.
(a) Describe the formation of a protein from \(\alpha\)-amino acids. In your answer, include the name and structure of the linkage formed between the monomers.
(b) A tripeptide is formed from three units of glycine (aminoethanoic acid, \(H_2NCH_2COOH\)).
(i) Draw the structure of this tripeptide.
(ii) Calculate the relative molecular mass (\(M_r\)) of the tripeptide. (\(A_r: H=1.0, C=12.0, N=14.0, O=16.0\))
(c) Proteins can be hydrolyzed to recover their constituent amino acids. State the reagents and conditions required for the complete hydrolysis of a protein in a laboratory setting.
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